Modeling human diseases in C. elegans
PREDOCTORAL RESEARCHERS (R1)
- David Ricardo Ahumada Brena
- Carmen Martinez Fernandez
- Xenia Serrat Farran
- Dmytro Kukthar
- Jeremy Vicencio Gumarao
Translational Medicine
Genes, Disease and Therapy
Scientific production
3
PAPERS
2 PUBLICATIONS IN FIRST QUARTILE
Selected publications
- Serrat X, Kukhtar D, Cornes E, Esteve-Codina A, Benlloch H, Cecere G, Cerón J*. CRISPR editing of sftb-1/SF3B1 in Caenorhabditis elegans allows the identification of synthetic interactions with cancer-related mutations and the chemical inhibition of splicing.. PLOS GENETICS. 10.1371/journal.pgen.1008464
- García-Moreno J.C., Porta de la Riva M., Martínez-Lara E., Siles E., Cañuelo A.. Tyrosol, a simple phenol from EVOO, targets multiple pathogenic mechanisms of neurodegeneration in a C. elegans model of Parkinson’s disease. NEUROBIOLOGY OF AGING. 10.1016/j.neurobiolaging.2019.07.003
- Vicencio J, Martínez-Fernández C, Serrat X, Cerón J *. Efficient Generation of Endogenous Fluorescent Reporters by Nested CRISPR in Caenorhabditis elegans.. GENETICS. 10.1534/genetics.119.301965
Research highlights
PROJECTS
4 Ongoing projects
PUBLISHED WORKS
1 Thesis
Selected projects
- C. elegans como modelo de enfermedades: uso de CRISPR/Cas9 para investigar respuestas a fármacos y patologías relacionadas con alteraciones en factores de splicing. (1/1/2016 – 30/11/2020) PI: CERON MADRIGAL, JULIAN. Funder: FIS-Instituto de Salud Carlos III.
- Genome editing as prognostic and therapeutic tool in human diseases (12/1/2018 – 11/1/2021) PI: CERON MADRIGAL, JULIAN. Funder: Fundació “La Caixa”.
- Optimización de CRISPR en C. elegans: nuevos reporteros y reemplazo de genes (1/4/2020 – 31/8/2020) PI: CERON MADRIGAL, JULIAN. Funder: MINISTERIO DE EDUCACION Y CIENCIA.