Hepato-biliary-pancreatic pathology

Jose Castellote Alonso

PRINCIPAL INVESTIGATORS
  • Joan Berenguer Gornals Soler
  • Juli Busquets Barenys
  • Joan Fabregat Prous
  • Emili Ramos Rubio
  • Carme Baliellas Comellas
  • Laura Llado Garriga
CLINICAL RESEARCHERS
  • Rosa Rota Roca
  • Teresa Serrano Pinol
  • Jaume Torras Torra
  • Antoni Rafecas Renau
  • Sandra Maisterra Santos
  • Francesc Bas Cutrina
  • Sandra Ruiz Osuna
  • Nuria Pelaez Serra
  • Luis Secanella Medayo
  • Albert Garcia Sumalla
Translational Medicine
Digestive system, diagnostics, pharmacogenetics, care support and clinical prevention

Scientific production

33

PAPERS

7 PUBLICATIONS IN FIRST DECILE

13 PUBLICATIONS IN FIRST QUARTILE

Selected publications

  • Busquets J, Martín S, Fabregat J, Secanella L, Pelaez N, Ramos E . Randomized trial of two types of gastrojejunostomy after pancreatoduodenectomy and risk of delayed gastric emptying (PAUDA trial).. BRITISH JOURNAL OF SURGERY. 10.1002/bjs.11023
  • Llado L., Ramos E., Bravo A., Baliellas C., Mils K., Busquets J., Cachero A., Secanella L., Pelaez N., Gonzalez-Vilatarsana E., Fabregat J.. Short- and long-term outcomes of arterial reconstruction on recipient splenic artery in adult liver transplantation. Single-center prospective study 25 years after first description. TRANSPLANT INTERNATIONAL. 10.1111/tri.13447
  • Martin-Cardona A., Fernandez-Esparrach G., Subtil J.C., Iglesias-Garcia J., Garcia-Guix M., Barroso A.B., Gimeno-Garcia A.Z., Esteban J.M., Balteiro A.P., Velasco-Guardado A., Vazquez-Sequeiros E., Loras C., Martinez-Moreno B., Castellot A., Huertas C., Martinez-Lapiedra M., Sanchez-Yague A., Teran A., Morales-Alvarado V.J., Betes M., de la Iglesia D., Sánchez-Montes C., Lozano M.D., Lariño-Noia J., Gines A., Tebe C., Gornals J.B.. EUS-guided tissue acquisition in the study of the adrenal glands: Results of a nationwide multicenter study. PLOS ONE. 10.1371/journal.pone.0216658
  • Gornals JB, Perez-Miranda M, Vazquez-Sequeiros E, Vila J, Esteban JM, Gonzalez-Huix F, Guarner-Argente C, Sanchez-Yague A, Teran A, Bas-Cutrina F, De La Serna C, De Paredes AG, Ballester R, Velasquez-Rodriguez J, Salord S, Tebe C, Hereu P, Videla S, Spanish Working Group on Pancreatic Collection Therapy. Multicenter study of plastic vs. self-expanding metal stents in endoscopic ultrasound-guided drainage of walled-off pancreatic necrosis – PROMETHEUS: A randomized controlled trial protocol. TRIALS. 10.1186/s13063-019-3988-x
  • Curieses Luengo M, Consiglieri CF, Puga M, Gornals JB . A novel rescue maneuver for a distal dislodged lumen-apposing metal stent (LAMS): “LAMS-in-LAMS” technique.. REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS. 10.17235/reed.2019.5924/2018

Research highlights

PROJECTS

1 Ongoing project
1 Started project

 

9 Ongoing clinical trials
4 Started clinical trials

PUBLISHED WORKS

1 Thesis

2 Clinical guidelines

Selected projects

  • BANDING-TSE: Valoración de la eficacia y seguridad de la ligadura con banda sin resección de tumores subepiteliales del tracto digestivo (- o =)15MM: Estudio multicéntrico prospectivo (1/12/2019 – 30/11/2021) PI: BAS CUTRINA, FRANCESC. Funder: Fundación SEED- Fundación Española de Endoscòpia Digestiva (FSEED).
  • Estudio multicéntrico, aleatorizado, abierto y de 12 meses de duración de la seguridad, eficacia, farmacocinética (PK) y farmacodinámica (PD) de dos pautas posológicas del anticuerpo nonoclonal anti-CD40, CFZ533, frente al tratamiento estándar en receptores adultos de trasplante hepático de novo con un seguimineto adicional de 12 meses (Contrail I) (4/4/2019 – ) PI: LLADO GARRIGA, LAURA. Funder ref.: CCFZ533A2202.
  • An open-label study to evaluate safety, efficacy and pharmacokinetics (PK) of Patisiran-LNP in patients with hereditary transthyretin-mediated amyloidosis (HATTR amyloidosis) with disease progression post-orthotopic liver transplant (5/4/2019 – ) PI: LLADO GARRIGA, LAURA. Funder ref.: ALN-TTR02-008.
  • A retrospective study to evaluate the epidemiology, standard of care, outcomes and resource use in patients with chronic liver disease associated thrombocytopenia in spain, using electronic health records and big data techniques (21/10/2019 – ) PI: CASTELLOTE ALONSO, JOSE. Funder ref.: SHI-HEP-2019-01.
  • A phase 2, double-blind, randomized, parallel-group study evaluating the efficacy, safety, and tolerability of obeticholic acid, administered alone or in combination with bezafibrate, in subjects with primary biliary cholangitis who had an inadequate response or who were unable to tolerate ursodeoxycholic acid (20/11/2019 – ) PI: CASTELLOTE ALONSO, JOSE. Funder ref.: 747-213.
  • Efectos sobre la mortalidad de la administración de albúmina en pacientes con cirrosis y encefalopatía hepática (22/2/2018 – 22/2/2022) PI: CASTELLOTE ALONSO, JOSE. Funder ref.: BETA.