Innate Immunity and Pathology of the Critical patient
Rafael Mañez Mendiluce
PRINCIPAL INVESTIGATORS
- Joan Sabater Riera
- Cristina Costa Valles
CLINICAL RESEARCHERS
- Juan Carlos Lopez Delgado
- Francisco Esteve Urbano
- Marta Huguet Briva
- Luisa Corral Ansa
- Gabriel Jesús Moreno Gonzalez
PREDOCTORAL RESEARCHERS (R1)
- Ricard Soley Corderas
- Sara Olivera Ardid
- Victor Daniel Gumucio Sanguino
SCIENTIFIC SUPPORT
- Kelly Casós Vásquez
- Leila González Barrera
Translational Medicine
Infectious disease and transplantation
Scientific production
17
PAPERS
4 PUBLICATIONS IN FIRST DECILE
6 PUBLICATIONS IN FIRST QUARTILE
Selected publications
- Blot, Stijn; Antonelli, Massimo; Arvaniti, Kostoula; Blot, Koen; Creagh-Brown, Ben; [+500 authors], Douglas; Naylor, Amanda; Lee, Sarah; Brevard, Sidney; Davis, Noelle;European Soc Intensive Care Med. Epidemiology of intra-abdominal infection and sepsis in critically ill patients: “AbSeS”, a multinational observational cohort study and ESICM Trials Group Project. INTENSIVE CARE MEDICINE. 10.1007/s00134-019-05819-3
- Bauer, Philippe R.; Chevret, Sylvie; Yadav, Hemang; Mehta, Sangeeta; Pickkers, Peter; [71 authors]; Gaborit, Benjamin; Viana, William N.; de Moraes, Ana Paula P.; Moralez, Guilliana M.; Vinatier, Isabelle;Efraim Investigators Nine-I Study. Diagnosis and outcome of acute respiratory failure in immunocompromised patients after bronchoscopy. EUROPEAN RESPIRATORY JOURNAL. 10.1183/13993003.02442-2018
- Bello-Gil, Daniel; Audebert, Christophe; Olivera-Ardid, Sara; Perez-Cruz, Magdiel; Even, Gael; Khasbiullina, Nailya; Gantois, Nausicaa; Shilova, Nadezhda; Merlin, Sophie; Costa, Cristina; Bovin, Nicolai; Manez, Rafael;. The Formation of Glycan-Specific Natural Antibodies Repertoire in GaIT-KO Mice Is Determined by Gut Microbiota. FRONTIERS IN IMMUNOLOGY. 10.3389/fimmu.2019.00342
- Lopez-Delgado J.C., Muñoz-del Rio G., Flordelís-Lasierra J.L., Putzu A.. Nutrition in Adult Cardiac Surgery: Preoperative Evaluation, Management in the Postoperative Period, and Clinical Implications for Outcomes. JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA. 10.1053/j.jvca.2019.04.002
- Olivera-Ardid S, Khasbiullina N, Nokel A, Formanovsky A, Popova I, Tyrtysh T, Kunetskiy R, Shilova N, Bovin N, Bello-Gil D, Mañez R . Printed Glycan Array: A Sensitive Technique for the Analysis of the Repertoire of Circulating Anti-carbohydrate Antibodies in Small Animals.. JOURNAL OF VISUALIZED EXPERIMENTS : JOVE. 10.3791/57662
Research highlights
PROJECTS
3 ongoing projects
2 started project
8 ongoing clinical trials
PUBLISHED WORKS
1 Clinical guideline
INNOVATION
1 Patent
1 license
1 spin-off
Selected projects
- Papel de los anticuerpos naturales anticarbohidrato en el desarrollo de infecciones nosocomiales por gérmenes gram-negativos multiresistentes (1/1/2018 – 31/12/2020) PI: MAÑEZ MENDILUCE, RAFAEL. Funder: FIS-Instituto de Salud Carlos III.
- SeptiLoop (Kit diagnòstic ràpid que identifica les infeccions bacterianes a la sang a través de l’activitat inmune. Aquesta eina de diagnóstic ajuda als metges d’emergencia a prendre millors decisions clíniques i optimizar el maneig de la sèpsia) (1/5/2019 – 31/10/2020) PI: SABATER RIERA, JOAN. Funder: AGAUR-GENERAL.CATALUNYA.
- Prevención de Infecciones Bacterianas Gram-Negativas Mediante la Eliminación de Anticuerpos Naturales Dirigidos a los Epítopos de α-Galactosil (αGal) (1/6/2019 – 31/5/2021) PI: MAÑEZ MENDILUCE, RAFAEL. Funder: MINISTERIO DE EDUCACION Y CIENCIA.
- A multicenter, double-blind, randomized, compartive study of the safety, tolerability, efficacy, and pharmacokinetics of cf-301 vs. placebo in addition to standard-of-care antibacterial therapy for the treatment of adult patients with staphylococcus aureus bloodstream infections (bacteremia) including right sided endocarditis (16/4/2018 – 16/4/2020) PI: MAÑEZ MENDILUCE, RAFAEL. Funder ref.: CF-301-102.
- Estudio aleatorizado doble ciego controlado con placebo de aerunica como terapia adyuvante a los antibioticos en el tratamiento de la neumonía por p. aeruginosa (12/2/2018 – ) PI: MAÑEZ MENDILUCE, RAFAEL. Funder ref.: AR-105-002.
- A phase 2, randomized, double-blind, placebo-controlled study to determine the safety and efficacy of a single dose of ASN100 for the prevention of staphylococcus aureus pheumonia in heavily colonized, mechanically ventilated subjects (24/5/2018 – ) PI: MAÑEZ MENDILUCE, RAFAEL. Funder ref.: ASN100-201.