Stem cells and Neurodegenerative diseases

Antonella Consiglio

COLLABORATORS
  • Eugenia Martinez Hernandez
POSTDOCTORAL RESEARCHERS (R2)
  • Alba Tristán Noguero
  • Carles Calatayud Aristoy
  • Meritxell Pons Espinal
PREDOCTORAL RESEARCHERS (R1)
  • Lucas Blasco Agell
  • Silvia Beltramone
  • Giulia Carola
  • Valentina Baruffi
SCIENTIFIC SUPPORT
  • Irene Fernandez Carasa
  • Isabel Turpin Moreno
Neuroscience
Neuroscience

Scientific production

8

PAPERS

2 PUBLICATIONS IN FIRST DECILE

7 PUBLICATIONS IN FIRST QUARTILE

Selected publications

  • Cai R., Zhang Y., Simmering J.E., Schultz J.L., Li Y., Fernandez-Carasa I., Consiglio A., Raya A., Polgreen P.M., Narayanan N.S., Yuan Y., Chen Z., Su W., Han Y., Zhao C., Gao L., Ji X., Welsh M.J., Liu L.. Enhancing glycolysis attenuates Parkinson’s disease progression in models and clinical databases. JOURNAL OF CLINICAL INVESTIGATION. 10.1172/JCI129987
  • Requena J, Alvarez-Palomo AB, Codina-Pascual M, Delgado-Morales R, Moran S, Esteller M, Sal M, Juan M, Boronat Barado A, Consiglio A, Bogle OA, Wolvetang E, Ovchinnikov D, Alvarez I, Jaraquemada D, Mezquita-Pla J, Oliva R, Edel MJ . Global Proteomic and Methylome Analysis in Human Induced Pluripotent Stem Cells Reveals Overexpression of a Human TLR3 Affecting Proper Innate Immune Response Signaling.. STEM CELLS. 10.1002/stem.2966
  • di Domenico A, Carola G, Calatayud C, Pons-Espinal M, Muñoz JP, Richaud-Patin Y, Fernandez-Carasa I, Gut M, Faella A, Parameswaran J, Soriano J, Ferrer I, Tolosa E, Zorzano A, Cuervo AM, Raya A, Consiglio A . Patient-Specific iPSC-Derived Astrocytes Contribute to Non-Cell-Autonomous Neurodegeneration in Parkinson’s Disease.. STEM CELL REPORTS. 10.1016/j.stemcr.2018.12.011
  • Fernández-Santiago R, Merkel A, Castellano G, Heath S, Raya Á, Tolosa E, Martí MJ, Consiglio A, Ezquerra M . Whole-genome DNA hyper-methylation in iPSC-derived dopaminergic neurons from Parkinson’s disease patients.. CLINICAL EPIGENETICS. 10.1186/s13148-019-0701-6
  • Calatayud C., Carola G., Fernández-Carasa I., Valtorta M., Jiménez-Delgado S., Díaz M., Soriano-Fradera J., Cappelletti G., García-Sancho J., Raya Á., Consiglio A.. CRISPR/Cas9-mediated generation of a tyrosine hydroxylase reporter iPSC line for live imaging and isolation of dopaminergic neurons. SCIENTIFIC REPORTS. 10.1038/s41598-019-43080-2
PROJECTS

2 ongoing projects
1 started project

PUBLISHED WORKS

2 Theses

Selected projects

  • Role of astrocytes on neuroinflammation pathogenesis in a human model of Parkinson’s disease. (1/4/2019 – 31/3/2021) PI: ANTONELLA CONSIGLIO CONSIGLIO. Funder: AGAUR-GENERAL.CATALUNYA.
  • Molecular, cellular and functional characterization of Parkinson’s disease patient-specific iPS cell-derived dopaminergic neurons (2017 – 2019) PI: CONSIGLIO CONSIGLIO, ANTONELLA. Funder: Spanish Research Ministry.