Neuropharmacology and pain

Francisco Ciruela Alferez

PRINCIPAL INVESTIGATORS
  • Xavier Altafaj Tardio
  • Concepcio Soler Prat
  • Sonia Forcales Fernández
  • Ester Aso Pérez
CLINICAL RESEARCHERS
  • Antoni Vallano Ferraz
  • Sebastián Videla Cés
  • Pilar Hereu Boher
COLLABORATORS
  • Maria Laura Cuffí Chéliz
  • Kristoffer Sahlholm
POSTDOCTORAL RESEARCHERS (R2)
  • Víctor Fernández Dueñas
  • Xavier Morato Arus
PREDOCTORAL RESEARCHERS (R1)
  • Marc Lopez Cano
  • Héctor Godoy Marín
  • Ana Santos Gomez
  • Marta Valle León
  • Josep Argerich Bergadà
  • René Crans
  • Roberta Celli
  • Laura Gómez Acero
SCIENTIFIC SUPPORT
  • Maria Salut Sanchez Rodriguez
  • Sílvia Locubiche Serra
  • Alex Fernandez Solanas
Neuroscience
Neuroscience

Scientific production

25

PAPERS

3 PUBLICATIONS IN FIRST DECILE

9 PUBLICATIONS IN FIRST QUARTILE

Selected publications:

  • Soto D, Olivella M, Grau C, Armstrong J, Alcon C, Gasull X, Santos-Gómez A, Locubiche S, Gómez de Salazar M, García-Díaz R, Gratacòs-Batlle E, Ramos-Vicente D, Chu-Van E, Colsch B, Fernández-Dueñas V, Ciruela F, Bayés À, Sindreu C, López-Sala A, García-Cazorla À, Altafaj X . L-Serine dietary supplementation is associated with clinical improvement of loss-of-function GRIN2B-related pediatric encephalopathy.. SCIENCE SIGNALING. 10.1126/scisignal.aaw0936
  • Lanznaster, Debora; Massari, Caio M.; Markova, Vendula; Simkova, Tereza; Duroux, Romain; Jacobson, Kenneth A.; Fernandez-Duenas, Victor; Tasca, Carla, I; Ciruela, Francisco;. Adenosine A(1)-A(2A) Receptor-Receptor Interaction: Contribution to Guanosine-Mediated Effects. CELLS. 10.3390/cells8121630
  • Morató X, Gonçalves FQ, Lopes JP, Jauregui O, Soler C, Fernández-Dueñas V, Cunha RA, Ciruela F . Chronic adenosine A2A receptor blockade induces locomotor sensitization and potentiates striatal LTD IN GPR37-deficient mice.. JOURNAL OF NEUROCHEMISTRY. 10.1111/jnc.14653
  • Aso E, Fernández-Dueñas V, López-Cano M, Taura J, Watanabe M, Ferrer I, Luján R, Ciruela F . Adenosine A2A-Cannabinoid CB1 Receptor Heteromers in the Hippocampus: Cannabidiol Blunts Δ9-Tetrahydrocannabinol-Induced Cognitive Impairment.. MOLECULAR NEUROBIOLOGY. 10.1007/s12035-018-1456-3
  • Esteve P, Rueda-Carrasco J, Inés Mateo M, Martin-Bermejo MJ, Draffin J, Pereyra G, Sandonís Á, Crespo I, Moreno I, Aso E, Garcia-Esparcia P, Gomez-Tortosa E, Rábano A, Fortea J, Alcolea D, Lleo A, Heneka MT, Valpuesta JM, Esteban JA, Ferrer I, Domínguez M, Bovolenta P . Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer’s disease pathogenesis.. NATURE NEUROSCIENCE. 10.1038/s41593-019-0432-1

Research highlights

PROJECTS

5 Ongoing projects

1 Ongoing clinical trial

PUBLISHED WORKS

2 Theses

Selected projects

  • Adenosine receptors as new targets for the treatment of atrial fibrillation: Biomarker, Risk-Stratification and Therapy (1/1/2017 – 31/12/2019) PI: CIRUELA ALFéREZ, FRANCISCO. Funder: Fundació La Marató de TV3.
  • Mutaciones de novo de los receptores NMDA asociadas a discapacidad intelectual y epilepsia: impacto patofisiológico, estratificación y farmacoterapia personalizada (24/3/2016 – 23/3/2019) PI: ALTAFAJ TARDIO, XAVIER. Funder: FIS-Instituto de Salud Carlos III.
  • Repetitive levosimendan infusions for patients with advanced chronic heart failure (Leodor) (20/7/2018 – ) PI: HEREU BOHER, PILAR. Funder ref.: LEODOR.